ABSTRACT
To compare the automated detection of malaria with microscopy. In this study 250 blood samples submitted for malaria investigation were studied microscopically for malaria parasites. All samples were additionally analyzed for same parameters with automated hematology analyzer, Cell Dyn 3700 [CD3700]. The results from the instrument generated as scatter plots [derived by laser light depolarization], were compared with microscopy results. The atypical depolarizing events or positive patterns were observed in 43 out of 250 samples on cell Dyn 3700, while microscopically 3 7 samples were found to b e positive. Three samples positive on microscopy, were found t o b e negative on CD-3700. Compared with microscopy the sensitivity of CD3700 was 92.5% and specificity was 97.3%. Maximum parasitaemia was 6.5%. Automated detection of malaria by CD3700 automated hematology analyzer is feasible for screening purpose in malaria endemic and non-endemic areas
Subject(s)
Humans , Microscopy , Pattern Recognition, Automated , Parasitemia , Mass Screening , Anopheles , Plasmodium falciparum , Plasmodium vivax , Plasmodium ovale , Plasmodium malariae , Sensitivity and SpecificityABSTRACT
In this study, 250 blood samples submitted for malaria investigation were studied microscopically for malarial parasites and platelet count. All samples were additionally analyzed for platelet count with automated haematology analyzer. Thirty seven [37] samples were found to be malaria positive microscopically. Out of 37 cases with malaria positive microscopically, thrombocytopenia was observed in 24 [64%] cases of malaria. So there is association of thrombocytopenia with malaria